Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.36 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924367 | 0.94 | PLA2G10 (0.36) | PLA2G10PLA2G5RAMP1CALCRLDPP7 | |
| SCHEMBL10792820 | 0.82 | PLA2G10 (0.38) | PLA2G10PLA2G5RAMP1CALCRLL3MBTL1 | |
| SCHEMBL7594489 | 0.81 | KMT2A (0.44) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7594492 | 0.81 | KMT2A (0.44) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL10914477 | 0.79 | PLA2G10 (0.38) | PLA2G10PLA2G5RAMP1CALCRLKDM4E | |
| SCHEMBL13929747 | 0.77 | RAMP1 (0.50) | PLA2G10PLA2G5RAMP1CALCRLL3MBTL1 | |
| SCHEMBL8921216 | 0.77 | RAMP1 (0.50) | PLA2G10PLA2G5RAMP1CALCRLL3MBTL1 | |
| SCHEMBL7488258 | 0.76 | ACE (0.36) | L3MBTL1DPP7ALDH1A1 | |
| SCHEMBL7488263 | 0.76 | ACE (0.36) | L3MBTL1DPP7ALDH1A1 | |
| SCHEMBL8921440 | 0.76 | PLA2G10 (0.40) | PLA2G10PLA2G5RAMP1CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279350-B1 | Fused azepinone and azocinone derivatives , process for their preparation, agents containing them and their use, as well as their intermediates during their production | HOECHST AG (DE) | 1993-12-01 | — | — | EP | disclosed |
| US-4857520-A | Fused azepinone and azocinone derivatives, processes for their preparation, agents containing them and their use, and intermediates in their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-15 | — | — | US | disclosed |
| EP-0279350-A2 | Fused azepinone and azocinone derivatives , process for their preparation, agents containing them and their use, as well as their intermediates during their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-24 | — | — | EP | disclosed |