Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HCAR3 | P49019 | 10/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.47 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18961357 | 0.88 | MAPT (0.44) | MAPTHCAR3GABRA5ALDH1A1L3MBTL1 | |
| SCHEMBL18940470 | 0.84 | CA12 (0.53) | MAPTALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL1680993 | 0.83 | MAPT (0.53) | MAPTHCAR3P4HTMP4HA1MIF | |
| SCHEMBL28210136 | 0.81 | MAPT (0.53) | MAPTHCAR3P4HTMP4HA1MIF | |
| SCHEMBL2818852 | 0.81 | MAPT (0.51) | MAPTHCAR3P4HTMP4HA1MIF | |
| SCHEMBL2421993 | 0.81 | NR4A2 (0.53) | MAPTP4HTMP4HA1MIFTSHR | |
| SCHEMBL344135 | 0.80 | MAPT (0.58) | MAPTHCAR3P4HTMP4HA1MIF | |
| SCHEMBL14811677 | 0.80 | MAPT (0.50) | MAPTHCAR3P4HTMP4HA1MIF | |
| SCHEMBL9566737 | 0.80 | NPC1 (0.57) | P4HTMGABRA5ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL841768 | 0.80 | L3MBTL1 (0.61) | MAPTP4HTMP4HA1MIFGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079466-A | 4-or 5-(sulphur) acylimino-and (inferior sulphur) amidopyridine and pyridine-N-oxide thereof | HOECHST AG (DE) | 1993-12-15 | — | — | CN | disclosed |
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |