Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59255 | 0.92 | ALDH1A1 (0.79) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL9770273 | 0.92 | ALDH1A1 (0.79) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL9216592 | 0.92 | ALDH1A1 (0.79) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL9770250 | 0.92 | ALDH1A1 (0.79) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL9066045 | 0.89 | ALDH1A1 (0.56) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL2457943 | 0.88 | TSHR (0.77) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL14337074 | 0.85 | TSHR (0.55) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL10593976 | 0.84 | ALDH1A1 (0.67) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL9219907 | 0.84 | ALDH1A1 (0.76) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL30305694 | 0.79 | TSHR (0.74) | TSHRALDH1A1LMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365483-B1 | Mercaptobenzoic-acid esters used as stabilizers for chlorine-containing polymers | CIBA GEIGY AG (CH) | 1993-12-29 | — | — | EP | claimed |
| US-5030671-A | Metal carboxylate and/or phenolate mixture | CIBA-GEIGY CORPORATION (US) | 1991-07-09 | — | — | US | claimed |
| US-5030671-A | Metal carboxylate and/or phenolate mixture | CIBA-GEIGY CORPORATION (US) | 1991-07-09 | — | — | US | disclosed |