Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514442 | 0.81 | PPARA (0.33) | — | |
| SCHEMBL9514170 | 0.78 | FFAR1 (0.32) | — | |
| SCHEMBL9516406 | 0.78 | CYSLTR2 (0.41) | — | |
| SCHEMBL9683488 | 0.75 | GRIN2B (0.40) | GRIN2BHDAC4KIF11 | |
| SCHEMBL9517894 | 0.74 | CYP2C9 (0.37) | — | |
| SCHEMBL9516779 | 0.72 | CYSLTR2 (0.35) | — | |
| SCHEMBL9683216 | 0.70 | TSHR (0.35) | — | |
| SCHEMBL5696804 | 0.69 | TDP1 (0.35) | GRIN2BHDAC4L3MBTL1 | |
| SCHEMBL8069408 | 0.68 | HDAC4 (0.38) | HDAC4L3MBTL1 | |
| SCHEMBL20594629 | 0.64 | FFAR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381728-B1 | DIFLUOROMETHYL COMPOUNDS | MERCK PATENT GMBH (DE) | 1993-12-08 | — | — | EP | disclosed |