Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 11/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900832 | 0.81 | MEN1 (0.37) | THRBTDP1CRHBPCRHR2 | |
| SCHEMBL9681362 | 0.80 | KMT2A (0.42) | TDP1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL5696804 | 0.77 | TDP1 (0.35) | GRIN2BHDAC4TDP1 | |
| SCHEMBL9515829 | 0.75 | GRIN2B (0.33) | GRIN2BHDAC4KIF11 | |
| SCHEMBL3443313 | 0.73 | ALDH1A1 (0.39) | GRIN2B | |
| SCHEMBL9330548 | 0.73 | KDM4E (0.40) | THRBTDP1OPRK1CRHBPCRHR2 | |
| SCHEMBL20957985 | 0.72 | ALDH1A1 (0.54) | TDP1 | |
| SCHEMBL9152803 | 0.71 | MEN1 (0.47) | OPRK1 | |
| SCHEMBL9683566 | 0.70 | NPSR1 (0.33) | THRBTDP1OPRM1OPRD1OPRK1 | |
| SCHEMBL9003583 | 0.69 | THRB (0.33) | THRBTDP1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089590-A | LIQUID CRYSTALLINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS MODIFIERS FOR POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-5084549-A | Aromatic polyesters as thermoplastic molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-28 | — | — | US | disclosed |
| EP-0354347-A2 | Liquid crystal compounds,their manufacture as modifiers for polycarbonates,polyestercarbonates and polyesters | BAYER AG (DE) | 1990-02-14 | — | — | EP | disclosed |