Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HPGDS | O60760 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519516 | 0.89 | HTT (0.60) | P4HTMLMNAL3MBTL1HPGDSALDH1A1 | |
| SCHEMBL9517800 | 0.87 | NPC1 (0.52) | P4HTMHDAC2HDAC8HDAC6NAMPT | |
| SCHEMBL9517200 | 0.87 | P4HTM (0.70) | P4HTMLMNAL3MBTL1 | |
| SCHEMBL9517097 | 0.86 | HSP90AA1 (0.51) | P4HTMHDAC2HDAC8HDAC6NAMPT | |
| SCHEMBL9515715 | 0.86 | MEN1 (0.54) | P4HTMCA2LMNAHDAC2HDAC8 | |
| SCHEMBL9519274 | 0.86 | SCN3A (0.51) | SCN3AP4HTMCA2LMNAL3MBTL1 | |
| SCHEMBL9137831 | 0.85 | P4HTM (0.73) | SCN3AP4HTMCA2LMNAL3MBTL1 | |
| SCHEMBL9516083 | 0.85 | P4HTM (0.60) | P4HTMLMNAL3MBTL1 | |
| SCHEMBL9519106 | 0.84 | EGFR (0.50) | P4HTM | |
| SCHEMBL9517987 | 0.83 | P4HTM (0.55) | P4HTMCA2LMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079466-A | 4-or 5-(sulphur) acylimino-and (inferior sulphur) amidopyridine and pyridine-N-oxide thereof | HOECHST AG (DE) | 1993-12-15 | — | — | CN | disclosed |
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |