Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.60 |
| ▸ | BCL2L1 | Q07817 | 10/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 10/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517200 | 0.92 | P4HTM (0.70) | P4HTMBCL2L1MCL1EGFRPTGS2 | |
| SCHEMBL9519730 | 0.87 | MCL1 (0.62) | P4HTMBCL2L1MCL1EGFR | |
| SCHEMBL9517987 | 0.86 | P4HTM (0.55) | P4HTMPTGS2MEN1LMNAKMT2A | |
| SCHEMBL9517238 | 0.86 | P4HTM (0.55) | P4HTMBCL2L1MCL1EGFRPTGS2 | |
| SCHEMBL9516101 | 0.85 | SCN3A (0.56) | P4HTMLMNAL3MBTL1 | |
| SCHEMBL9517993 | 0.85 | PTGS2 (0.59) | P4HTMEGFRPTGS2PTGS1KMT2A | |
| SCHEMBL9515762 | 0.84 | P4HTM (0.49) | P4HTMMEN1KMT2AL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL27452745 | 0.83 | P4HTM (0.52) | P4HTMBCL2L1MCL1EGFRPTGS2 | |
| SCHEMBL9515727 | 0.83 | P4HTM (0.51) | P4HTMBCL2L1MCL1EGFRMEN1 | |
| SCHEMBL9519310 | 0.82 | EGFR (0.51) | P4HTMBCL2L1MCL1EGFRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |