Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517563 | 0.88 | L3MBTL1 (0.41) | TSHRSLC1A1KMT2AMEN1ALDH1A1 | |
| SCHEMBL732892 | 0.82 | TSHR (0.57) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL8686256 | 0.80 | TSHR (0.55) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL28360019 | 0.76 | TSHR (0.50) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL9602992 | 0.75 | TSHR (0.48) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL9602990 | 0.75 | TSHR (0.48) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL3239453 | 0.75 | TSHR (0.48) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL14066245 | 0.73 | TSHR (0.46) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL11592937 | 0.72 | TSHR (0.58) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL10012535 | 0.72 | TSHR (0.50) | TSHRSLC1A1KMT2AMEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378073-B1 | PROCESS FOR THE PREPARATION OF 1,3-CYCLOPENTANDIONE | LONZA AG (CH) | 1993-05-19 | — | — | EP | claimed |