Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 8/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.52 |
| ▸ | TUBB | P07437 | 3/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415279 | 0.86 | IDO1 (0.51) | HTR2ATRPM8IDO1TUBB4ATUBB | |
| SCHEMBL9514779 | 0.78 | STAT3 (0.59) | HTR2AIDO1TUBB4ATUBBTUBA3C | |
| SCHEMBL9516255 | 0.77 | HTR2A (0.61) | HTR2ATRPM8IDO1TUBB4ATUBB | |
| SCHEMBL1399487 | 0.77 | HTR2A (0.65) | HTR2ATRPM8IDO1TUBB4ATUBB | |
| Hydrochloric Acid SCHEMBL10681278 | 0.77 | STAT3 (0.58) | HTR2AIDO1TUBB4ATUBBTUBA3C | |
| SCHEMBL11612855 | 0.76 | IDO1 (0.62) | HTR2ATRPM8IDO1TUBB4ATUBB | |
| SCHEMBL28381230 | 0.75 | IDO1 (0.54) | HTR2ATRPM8IDO1TUBB4ATUBB | |
| SCHEMBL1399216 | 0.75 | IDO1 (0.62) | HTR2ATRPM8IDO1TUBB4ATUBB | |
| SCHEMBL951250 | 0.74 | NR4A2 (0.44) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30724496 | 0.73 | HTR2A (1.00) | HTR2ATRPM8GPR84MAPTSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227488-A | AZA SPIRO DECANE AND USE THEREOF IN TREATING CNS DISORDERS | NOVO NORDISK A/S (DK) | 1993-07-13 | — | — | US | disclosed |
| EP-0495826-A1 | INDOLE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-07-29 | — | — | EP | disclosed |
| WO-1991004973-A1 | INDOLE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-04-18 | — | — | WO | disclosed |