SCHEMBL9516282

SCHEMBL9516282

NC(=O)C[S+]([O-])CC(N)=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.37
BLM P54132 3/20 0.37
CYP3A4 P08684 2/20 0.37
PMP22 Q01453 2/20 0.37
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GMNN O75496 1/20 0.37
USP2 O75604 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
GLA P06280 1/20 0.37
POLB P06746 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
CYP2C19 P33261 1/20 0.37
THPO P40225 1/20 0.37
RECQL P46063 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylamine SCHEMBL28180135 0.91 LMNA (0.32) LMNABLMCYP3A4PMP22ALDH1A1
SCHEMBL9031476 0.89 GLRA1 (0.32) LMNABLMCYP3A4PMP22ALDH1A1
SCHEMBL8837089 0.83
SCHEMBL4417005 0.81
SCHEMBL11524316 0.77
SCHEMBL2476307 0.75
SCHEMBL1286839 0.69 LMNA (0.35) LMNAPMP22ALDH1A1ALOX15CYP2C19
SCHEMBL9996194 0.67 TSHR (0.31) TSHR
SCHEMBL1833885 0.67
Propionamide SCHEMBL4460082 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544657-A4 METHOD FOR MAKING UNIFORMLY-SIZED PARTICLES FROM INSOLUBLE COMPOUNDS 1993-08-04 EP disclosed
EP-0544657-A1 METHOD FOR MAKING UNIFORMLY-SIZED PARTICLES FROM INSOLUBLE COMPOUNDS THE UNIVERSITY OF ROCHESTER (US) 1993-06-09 EP disclosed
WO-1992003380-A1 METHOD FOR MAKING UNIFORMLY-SIZED PARTICLES FROM INSOLUBLE COMPOUNDS THE UNIVERSITY OF ROCHESTER (US) 1992-03-05 WO disclosed
EP-0157795-B1 STABILIZED POLYVINYL CHLORIDE MOULDING MATERIAL Henkel Kommanditgesellschaft auf Aktien (DE) 1988-07-20 EP disclosed
US-4656210-A Stabilized polyvinyl chloride molding compositions HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1987-04-07 US disclosed
EP-0157795-A1 STABILIZED POLYVINYL CHLORIDE MOULDING MATERIAL. HENKEL KGAA (DE) 1985-10-16 EP disclosed
WO-1985001054-A1 STABILIZED POLYVINYL CHLORIDE MOULDING MATERIAL HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1985-03-14 WO disclosed