Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GRM8 | O00222 | 1/20 | 0.30 |
| ▸ | GRM6 | O15303 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516626 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2HSD17B10NSD2KDM4EGRM4 | |
| SCHEMBL9516594 | 0.76 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL3147412 | 0.74 | SMN1; SMN2 (0.37) | SMN1; SMN2HSD17B10KDM4ETTR | |
| Water SCHEMBL5482872 | 0.72 | SMN1; SMN2 (0.36) | SMN1; SMN2HSD17B10KDM4ETTR | |
| Acetic Acid SCHEMBL8865239 | 0.68 | FFAR3 (0.54) | SMN1; SMN2HSD17B10KDM4EALDH1A1TTR | |
| Dioxane SCHEMBL29086945 | 0.68 | FFAR3 (0.54) | SMN1; SMN2HSD17B10KDM4EALDH1A1TTR | |
| Dioxane SCHEMBL21066036 | 0.68 | ACHE (0.54) | SMN1; SMN2HSD17B10KDM4EALDH1A1TTR | |
| Dioxane SCHEMBL575055 | 0.68 | FFAR3 (0.54) | SMN1; SMN2HSD17B10KDM4EALDH1A1TTR | |
| Dioxane SCHEMBL9684295 | 0.67 | TTR (0.55) | SMN1; SMN2HSD17B10KDM4EALDH1A1TTR | |
| Dioxane SCHEMBL3328113 | 0.67 | TTR (0.55) | SMN1; SMN2HSD17B10KDM4EALDH1A1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341409-B1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-12-29 | — | — | EP | claimed |