Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516689 | 1.00 | ALOX5 (0.62) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL9781084 | 1.00 | ALOX5 (0.62) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL9516692 | 1.00 | ALOX5 (0.62) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL9517929 | 0.86 | ALOX5 (0.47) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL9514443 | 0.86 | ALOX5 (0.47) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL9517925 | 0.86 | ALOX5 (0.47) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL9514434 | 0.86 | ALOX5 (0.47) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL9171356 | 0.83 | MAPT (0.47) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL8965561 | 0.79 | BCL2L1 (0.48) | ALOX5MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL8965558 | 0.79 | BCL2L1 (0.48) | ALOX5MAPTMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384594-B1 | Anti-inflammatory aryl derivatives | WELLCOME FOUND (GB) | 1993-10-27 | — | — | EP | disclosed |