Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17409935 | 0.81 | TSHR (0.50) | TSHRL3MBTL1ALDH1A1LMNAFPR2 | |
| SCHEMBL29779769 | 0.81 | L3MBTL1 (0.48) | TSHRL3MBTL1ALDH1A1LMNAPABPC1 | |
| SCHEMBL29779773 | 0.81 | L3MBTL1 (0.48) | TSHRL3MBTL1ALDH1A1LMNAPABPC1 | |
| SCHEMBL27547594 | 0.79 | TSHR (0.56) | TSHRL3MBTL1ALDH1A1LMNAPABPC1 | |
| SCHEMBL9359473 | 0.79 | TSHR (0.56) | TSHRL3MBTL1ALDH1A1LMNAPABPC1 | |
| SCHEMBL17526434 | 0.77 | L3MBTL1 (0.54) | TSHRL3MBTL1LMNAPABPC1APOBEC3A | |
| SCHEMBL17526818 | 0.77 | L3MBTL1 (0.54) | TSHRL3MBTL1LMNAPABPC1APOBEC3A | |
| SCHEMBL12459737 | 0.77 | TSHR (0.54) | TSHRL3MBTL1ALDH1A1LMNAPABPC1 | |
| SCHEMBL6820469 | 0.77 | L3MBTL1 (0.54) | TSHRL3MBTL1ALDH1A1LMNAPABPC1 | |
| SCHEMBL8136448 | 0.76 | TSHR (0.39) | TSHRL3MBTL1ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410241-B1 | Aryl alkenoic acid derivatives as leukotriene antagonists | BAYER AG (DE) | 1993-10-20 | — | — | EP | disclosed |
| EP-0410241-A1 | Aryl alkenoic acid derivatives as leukotriene antagonists | BAYER AG (DE) | 1991-01-30 | — | — | EP | disclosed |