Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | ITK | Q08881 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.39 |
| ▸ | PASK | Q96RG2 | 1/20 | 0.39 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.39 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872830 | 0.75 | MEN1 (0.50) | HTTSMN1; SMN2MAPTNPSR1KMT2A | |
| SCHEMBL6826636 | 0.74 | HTT (0.57) | HTTRAB9ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL4710342 | 0.74 | RAB9A (0.45) | RAB9AMAPTLMNAKMT2AMEN1 | |
| SCHEMBL15366075 | 0.73 | HTT (0.50) | HTTRAB9ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL8519255 | 0.71 | AR (0.36) | HTTRAB9AMAPK8MAPK9MAPK10 | |
| SCHEMBL9314849 | 0.71 | TDP1 (0.42) | RAB9AMAPTLMNAKMT2AMEN1 | |
| SCHEMBL6562681 | 0.70 | GAA (0.46) | HTTSMN1; SMN2MAPTNPSR1LMNA | |
| SCHEMBL11649742 | 0.69 | TDP1 (0.43) | RAB9AMAPTLMNAKMT2AMEN1 | |
| SCHEMBL4271625 | 0.69 | HTT (0.61) | HTTRAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL29674877 | 0.69 | HTT (0.66) | HTTRAB9ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455168-B1 | DYEING COMPOSITION FOR KERATIN FIBER | Kao Corporation (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-5089026-A | 1,5-Dihydroxynaphthalene, 2-amino-5-hydroxybenzoic acid, cosmetically acceptable base | KAO CORPORATION (JP) | 1992-02-18 | — | — | US | disclosed |
| EP-0455168-A1 | Dyeing composition for keratin fiber | Kao Corporation (JP) | 1991-11-06 | — | — | EP | disclosed |