Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.30 |
| ▸ | CHRNG | P07510 | 1/20 | 0.30 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.30 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | CHRND | Q07001 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515140 | 1.00 | SLC6A3 (0.31) | SLC6A3SLC6A4SLC6A2CHRNA1CHRNG | |
| SCHEMBL9515139 | 1.00 | SLC6A3 (0.31) | SLC6A3SLC6A4SLC6A2CHRNA1CHRNG | |
| SCHEMBL9580467 | 1.00 | SLC6A3 (0.31) | SLC6A3SLC6A4SLC6A2CHRNA1CHRNG | |
| SCHEMBL9515180 | 0.92 | KMT2A (0.32) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9516653 | 0.92 | KMT2A (0.32) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9515177 | 0.92 | KMT2A (0.32) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9516802 | 0.91 | RECQL (0.30) | — | |
| SCHEMBL9515751 | 0.91 | RECQL (0.30) | — | |
| SCHEMBL9515756 | 0.91 | RECQL (0.30) | — | |
| SCHEMBL9518897 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369762-B1 | Pesticides | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | claimed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | claimed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | claimed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |