Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517362 | 0.80 | MAPK1 (0.71) | MAPK1KDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL28786488 | 0.71 | MAPK1 (0.46) | MAPK1ALOX15KDM4EHPGDCYP1A2 | |
| SCHEMBL22761661 | 0.70 | HSD17B10 (0.59) | PTGS1PTGS2HSD17B10 | |
| SCHEMBL26054623 | 0.68 | MAPK1 (0.40) | MAPK1ALOX15KDM4EHPGDCYP1A2 | |
| SCHEMBL2865146 | 0.67 | CSNK1E (0.41) | SMN1; SMN2 | |
| SCHEMBL9516847 | 0.67 | MAPK1 (0.59) | MAPK1ALOX15CYP1A2TDP1ALOX12 | |
| SCHEMBL6891152 | 0.67 | KDM4E (0.38) | MAPK1PTGS1PTGS2KDM4EHPGD | |
| SCHEMBL12357158 | 0.66 | TDP1 (0.47) | MAPK1ALOX15KDM4EHPGDCYP1A2 | |
| SCHEMBL22761663 | 0.65 | HSD17B10 (0.44) | PTGS1PTGS2HSD17B10 | |
| Hydrochloric Acid SCHEMBL2246808 | 0.65 | TDP1 (0.46) | MAPK1ALOX15KDM4EHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238070-B1 | Sulfonylurea compounds, their production and herbicidal use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-5017212-A | For rice paddies | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0238070-A2 | Sulfonylurea compounds, their production and herbicidal use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |