SCHEMBL951685

SCHEMBL951685

OCc1ccc2[nH]ccc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.55
GAA P10253 1/20 0.55
ALOX15 P16050 1/20 0.55
RAD51 Q06609 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
AHR P35869 4/20 0.50
NR4A2 P43354 2/20 0.50
CYP2A6 P11509 2/20 0.50
F7 P08709 1/20 0.50
LTA4H P09960 1/20 0.50
F3 P13726 1/20 0.50
HDAC1 Q13547 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
CYP17A1 P05093 1/20 0.47
CYP11B1 P15538 1/20 0.47
CYP11B2 P19099 1/20 0.47
F2 P00734 1/20 0.47
IMPDH2 P12268 1/20 0.46
IMPDH1 P20839 1/20 0.46
NPC1 O15118 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30614296 1.00 USP2 (0.55) USP2GAAALOX15RAD51NPSR1
SCHEMBL7222368 0.84 HDAC1 (0.54) USP2GAAALOX15RAD51NPSR1
SCHEMBL1252105 0.83 TYR (0.55) USP2GAAALOX15RAD51NPSR1
SCHEMBL31241635 0.83 TYR (0.55) USP2GAAALOX15RAD51NPSR1
SCHEMBL8666600 0.83 HDAC1 (0.55) USP2GAAALOX15RAD51NPSR1
Ethoxycarbonyl Group SCHEMBL28291607 0.82 CYP2A6 (0.43) USP2GAAALOX15RAD51NPSR1
Tert-Butyl Formate SCHEMBL28290005 0.82 CYP2A6 (0.43) USP2GAAALOX15RAD51NPSR1
SCHEMBL14832829 0.81 HDAC1 (0.58) USP2GAAALOX15RAD51NPSR1
SCHEMBL9913530 0.79 NPC1 (0.44) USP2GAAALOX15RAD51NPSR1
SCHEMBL5057022 0.79 AHR (0.50) USP2GAAALOX15RAD51NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108828110-B Method for determining residual quantity of benzimidazole drugs in chicken fat 广东出入境检验检疫局检验检疫技术中心 2021-09-21 CN claimed
CN-109001334-B Method for measuring residual quantity of benzimidazole drugs in chicken tissues 广东出入境检验检疫局检验检疫技术中心 2021-04-27 CN claimed
WO-2002080906-A1 PREVENTION AND TREATMENT OF ENDOMETRIOSIS WITH ARYL HYDROCARBON RECEPTOR BINDING LIGANDS CEDARS-SINAI MEDICAL CENTER (US) 2002-10-17 WO claimed
US-20020147155-A1 Prevention and treatment of endometriosis with aryl hydrocarbon receptor binding ligands CEDARS-SINAI MEDICAL CENTER 2002-10-10 US claimed
CN-111251500-B Foaming polymer particles with skin dilatancy and preparation method thereof 厦门天策材料科技有限公司 2024-10-22 CN disclosed
CN-118359656-A Copper-catalyzed stannization reaction method for carbon-oxygen bond cleavage of aryl methanol 天津师范大学 2024-07-19 CN disclosed
US-12012411-B2 Viral replication inhibitors KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-06-18 US disclosed
EP-3345900-B1 2, 4-DI-(NITROGEN CONTAINING GROUP) SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF BEBETTER MED INC (CN) 2024-06-12 EP disclosed
CN-111253583-B Dilatant hybrid dynamic polymer and dilatant realization method thereof 厦门天策材料科技有限公司 2023-05-16 CN disclosed
CN-113754631-B Heteroaryl method of indole 中国科学院理化技术研究所 2022-08-30 CN disclosed
US-20220106321-A1 VIRAL REPLICATION INHIBITORS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2022-04-07 US disclosed
US-11279704-B2 Viral replication inhibitors KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2022-03-22 US disclosed
EP-0442820-B1 Benzimidazole and azabenzimidazole derivatives, thromboxane receptor antagonists, processes for their preparation, synthesis intermediates, compositions containing them UNION PHARMA SCIENT APPL (FR) 1995-09-13 EP disclosed
EP-0450345-B1 Indole derivatives MERCK PATENT GMBH (DE) 1995-05-24 EP disclosed
US-5227386-A INDOLE DERIVATIVES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-07-13 US disclosed
EP-0450345-A1 Indole derivatives MERCK PATENT GmbH (DE) 1991-10-09 EP disclosed
EP-0442820-A1 Benzimidazole and azabenzimidazole derivatives, thromboxane receptor antagonists, processes for their preparation, synthesis intermediates, compositions containing them LABORATOIRES UPSA (FR) 1991-08-21 EP disclosed
EP-0197294-B1 BETA-LACTAM ANTIBIOTICS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS BAYER AG (DE) 1991-04-03 EP disclosed
US-4734407-A ANIMAL GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1988-03-29 US disclosed
EP-0197294-A2 Beta-lactam antibiotics, process for their preparation and their use as medicaments BAYER AG (DE) 1986-10-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11279704-B2 Viral replication inhibitors EIF2AK2, MAVS, ZC3HAV1 USP2 2615/4885GAA 810/4885ALOX15 3293/4885
US-20220106321-A1 VIRAL REPLICATION INHIBITORS EIF2AK2, MAVS, ZC3HAV1 USP2 2615/4885GAA 810/4885ALOX15 3293/4885
US-12012411-B2 Viral replication inhibitors EIF2AK2, MAVS, ZC3HAV1 USP2 2615/4885GAA 810/4885ALOX15 3293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.