Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | APP | P05067 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | INSR | P06213 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516881 | 1.00 | MAPT (0.66) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL2526639 | 0.88 | MAPT (0.74) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL2526641 | 0.88 | MAPT (0.74) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL2830702 | 0.85 | MAPT (0.73) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL23111697 | 0.82 | MAPT (0.77) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL19695963 | 0.82 | MAPT (0.77) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9515558 | 0.81 | SNCA (0.60) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9515572 | 0.81 | SNCA (0.60) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL17576070 | 0.81 | MAPT (0.79) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL16180704 | 0.81 | MAPT (0.79) | MAPTKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0219436-A2 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |