Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515556 | 1.00 | CNR2 (0.51) | CNR2LMNASMN1; SMN2TDP1NPSR1 | |
| SCHEMBL9517246 | 0.93 | CNR2 (0.53) | CNR2TSHRSMPD1ALDH1A1CYSLTR1 | |
| SCHEMBL9519167 | 0.93 | CNR2 (0.53) | CNR2TSHRSMPD1ALDH1A1CYSLTR1 | |
| SCHEMBL9517977 | 0.89 | CA1 (0.52) | CNR2LMNASMN1; SMN2TSHRKMT2A | |
| SCHEMBL9515757 | 0.89 | CA1 (0.52) | CNR2LMNASMN1; SMN2TSHRKMT2A | |
| SCHEMBL9515761 | 0.88 | CA1 (0.53) | CNR2LMNASMN1; SMN2TSHRKMT2A | |
| SCHEMBL9517289 | 0.88 | MAPT (0.47) | CNR2LMNASMN1; SMN2KMT2AGAA | |
| SCHEMBL9517205 | 0.88 | PPARA (0.46) | SMN1; SMN2KMT2AGAA | |
| SCHEMBL9519339 | 0.88 | NPC1 (0.49) | CNR2SMN1; SMN2KMT2ACYSLTR1 | |
| SCHEMBL9515521 | 0.88 | MAPT (0.47) | CNR2LMNASMN1; SMN2KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |