Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517977 | 1.00 | CA1 (0.52) | CA1CA2CA7CA9CA14 | |
| SCHEMBL9515761 | 0.99 | CA1 (0.53) | CA1CA2CA7CA9CA14 | |
| SCHEMBL9517246 | 0.95 | CNR2 (0.53) | CA1CA2CA7CA9CA14 | |
| SCHEMBL9519167 | 0.95 | CNR2 (0.53) | CA1CA2CA7CA9CA14 | |
| SCHEMBL9515979 | 0.93 | ALDH1A1 (0.57) | CA1CA2CA7CA9CA14 | |
| SCHEMBL9516960 | 0.91 | KMT2A (0.49) | ALDH1A1MAPTCNR2KMT2ALMNA | |
| SCHEMBL9517171 | 0.91 | KMT2A (0.49) | ALDH1A1MAPTCNR2KMT2ALMNA | |
| SCHEMBL9518004 | 0.91 | KMT2A (0.49) | ALDH1A1MAPTCNR2KMT2ALMNA | |
| SCHEMBL9516967 | 0.90 | KMT2A (0.49) | ALDH1A1MAPTCNR2KMT2ALMNA | |
| SCHEMBL9516933 | 0.89 | CNR2 (0.51) | ALDH1A1CNR2GAATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |