Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.48 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517110 | 0.84 | P4HTM (0.61) | P4HTMPTGS2BCL2L1MCL1L3MBTL1 | |
| SCHEMBL9517114 | 0.84 | LIMK1 (0.47) | LIMK1LIMK2HDAC1HDAC6P4HTM | |
| SCHEMBL9519173 | 0.82 | P4HTM (0.58) | P4HTMGAAPTGS2BCL2L1MCL1 | |
| SCHEMBL9138602 | 0.81 | P4HTM (0.48) | LIMK1LIMK2HDAC1HDAC6P4HTM | |
| SCHEMBL9140979 | 0.80 | P4HTM (0.53) | LIMK1LIMK2HDAC1HDAC6P4HTM | |
| SCHEMBL9137310 | 0.80 | P4HTM (0.62) | LIMK1LIMK2HDAC1HDAC6P4HTM | |
| SCHEMBL9137000 | 0.80 | P4HTM (0.48) | LIMK1LIMK2HDAC1HDAC6P4HTM | |
| SCHEMBL8868783 | 0.78 | LIMK1 (0.48) | LIMK1LIMK2HDAC1HDAC6P4HTM | |
| SCHEMBL9517927 | 0.78 | P4HTM (0.42) | LIMK1LIMK2HDAC1HDAC6P4HTM | |
| SCHEMBL9137002 | 0.78 | P4HTM (0.48) | LIMK1LIMK2HDAC1HDAC6P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |