Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519173 | 0.90 | P4HTM (0.58) | P4HTMPTGS2BCL2L1MCL1EGFR | |
| SCHEMBL9517241 | 0.88 | P4HTM (0.61) | P4HTMPTGS2PTGS1BCL2L1MCL1 | |
| SCHEMBL9515933 | 0.87 | P4HTM (0.55) | P4HTMPTGS2PTGS1BCL2L1MCL1 | |
| SCHEMBL9517975 | 0.87 | P4HTM (0.53) | P4HTMCASP3LMNAKMT2AL3MBTL1 | |
| SCHEMBL9516016 | 0.86 | P4HTM (0.58) | P4HTMPTGS2PTGS1BCL2L1MCL1 | |
| SCHEMBL9516962 | 0.84 | LIMK1 (0.48) | P4HTMPTGS2BCL2L1MCL1EGFR | |
| SCHEMBL9515532 | 0.83 | P4HTM (0.61) | P4HTMPTGS2PTGS1BCL2L1MCL1 | |
| SCHEMBL9518145 | 0.83 | P4HTM (0.61) | P4HTMPTGS2PTGS1BCL2L1MCL1 | |
| SCHEMBL9517200 | 0.82 | P4HTM (0.70) | P4HTMPTGS2PTGS1BCL2L1MCL1 | |
| SCHEMBL9517040 | 0.82 | MEN1 (0.48) | MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |