Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.56 |
| ▸ | RAB9A | P51151 | 12/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423547 | 0.81 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL7883973 | 0.81 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL758876 | 0.81 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL9570362 | 0.81 | KDM4E (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL9043267 | 0.81 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL103805 | 0.81 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL5816677 | 0.81 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL859545 | 0.81 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL102061 | 0.81 | KDM4E (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| Ammonia Solution, Strong SCHEMBL1764260 | 0.79 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238070-B1 | Sulfonylurea compounds, their production and herbicidal use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-5017212-A | For rice paddies | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0238070-A2 | Sulfonylurea compounds, their production and herbicidal use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |