SCHEMBL9517101

SCHEMBL9517101

NC(C=O)C(=O)O.[NaH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25955 0.97
SCHEMBL334131 0.97
SCHEMBL28977853 0.97
Beta-Alanine SCHEMBL7631991 0.78 CYP1A2 (0.41)
Pyridine SCHEMBL28789704 0.78 TSHR (0.39)
SCHEMBL3864044 0.71
SCHEMBL5618632 0.71
SCHEMBL3925246 0.69
SCHEMBL27558180 0.69
SCHEMBL3513634 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0385999-B1 APPLICATION OF 4- 1-OXOALKYL]-2,5-OXAZOLIDINEDIONES IN SELECTIVE STEREOSPECIFIC FORMATION OF BIOLOGICALLY ACTIVE BETA-LACTAMS UNIV CINCINNATI (US) 1993-12-08 EP disclosed
US-5006661-A Selective stereospecific biologically active beta-lactams UNIVERSITY OF CINCINNATI (US) 1991-04-09 US disclosed
EP-0385999-A1 APPLICATION OF 4- 1-OXOALKYL]-2,5-OXAZOLIDINEDIONES IN SELECTIVE STEREOSPECIFIC FORMATION OF BIOLOGICALLY ACTIVE BETA-LACTAMS. UNIV CINCINNATI (US) 1990-09-12 EP disclosed
US-4855419-A Application of 4-[1-oxoalkyl]-2,5-oxazolidinediones in selective stereospecific formation of biologically active α-lactams UNIVERSITY OF CINCINNATI (US) 1989-08-08 US disclosed
WO-1988010256-A1 APPLICATION OF 4-[1-OXOALKYL]-2,5-OXAZOLIDINEDIONES IN SELECTIVE STEREOSPECIFIC FORMATION OF BIOLOGICALLY ACTIVE BETA-LACTAMS UNIVERSITY OF CINCINNATI (US) 1988-12-29 WO disclosed