Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517864 | 1.00 | KCNH2 (0.52) | KCNH2LMNAGAAMAPTPKM | |
| SCHEMBL9517159 | 1.00 | KCNH2 (0.52) | KCNH2LMNAGAAMAPTPKM | |
| SCHEMBL9517277 | 0.85 | HTR3E (0.51) | KCNH2MAPT | |
| SCHEMBL9517282 | 0.85 | HTR3E (0.51) | KCNH2MAPT | |
| SCHEMBL9517275 | 0.85 | HTR3E (0.51) | KCNH2MAPT | |
| SCHEMBL28277997 | 0.81 | KCNH2 (0.55) | KCNH2MAPTPKM | |
| SCHEMBL28278031 | 0.81 | KCNH2 (0.55) | KCNH2MAPTPKM | |
| SCHEMBL9517909 | 0.81 | POLB (0.49) | LMNAGAASMN1; SMN2TSHR | |
| SCHEMBL9518832 | 0.81 | POLB (0.49) | LMNAGAASMN1; SMN2TSHR | |
| SCHEMBL9592504 | 0.81 | POLB (0.49) | LMNAGAASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216141-A | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR LINKAGES | BENNER, STEVEN | 1993-06-01 | — | — | US | disclosed |
| EP-0418309-A4 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | — | 1993-01-07 | — | — | EP | disclosed |
| EP-0418309-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | BENNER, Steven Albert (CH) | 1991-03-27 | — | — | EP | disclosed |
| WO-1989012060-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | BENNER STEVEN ALBERT (CH) | 1989-12-14 | — | — | WO | disclosed |