Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM6A | O15550 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 8/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10480777 | 0.87 | PKM (0.54) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL9387565 | 0.85 | KDM4E (0.51) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL9351927 | 0.81 | KDM4E (0.57) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL12949574 | 0.76 | KDM4E (0.55) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL7150863 | 0.76 | KDM4E (0.46) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL5525055 | 0.76 | KDM4E (0.62) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL6949699 | 0.74 | KDM4E (0.53) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL9386339 | 0.73 | KDM4E (0.51) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL8102001 | 0.73 | KDM4E (0.51) | KDM4ETP53CYP2D6HTTSMN1; SMN2 | |
| SCHEMBL5085644 | 0.73 | KDM4E (0.58) | KDM4ETP53CYP2D6HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397409-B1 | THE STABILIZATION OF ORGANIC COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1993-07-21 | — | — | EP | disclosed |
| US-5185319-A | STABILIZATION OF ORGANIC COMPOUNDS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0397409-A1 | The stabilization of organic compounds | BTG INTERNATIONAL LIMITED (GB) | 1990-11-14 | — | — | EP | disclosed |