SCHEMBL9517356

SCHEMBL9517356

COc1ccc(SCCSc2ccc(OC)cc2OC)c(OC)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
CA14 Q9ULX7 1/20 0.54
ALDH1A1 P00352 5/20 0.52
CYP3A4 P08684 2/20 0.52
APLNR P35414 1/20 0.47
CYP1A1 P04798 5/20 0.47
CYP1A2 P05177 5/20 0.47
CYP1B1 Q16678 5/20 0.47
NPC1 O15118 1/20 0.43
MAPT P10636 4/20 0.43
CYP2E1 P05181 1/20 0.43
CYP2C8 P10632 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2A6 P11509 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP4B1 P13584 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3511278 0.79 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL25074911 0.78 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL3511274 0.78 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL6624870 0.77 NPC1 (0.47) CA12CA1CA2CA7CA9
SCHEMBL11986360 0.76 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL26944267 0.73 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL11986364 0.73 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL4431677 0.73 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL31460339 0.73 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL9517394 0.72 ALDH1A1 (0.43) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0345847-B1 PROCESS FOR THE PREPARATION OF POLYMERS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-08-04 EP disclosed
EP-0345847-A1 Process for the preparation of polymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-12-13 EP disclosed