Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8146619 | 1.00 | CYP2D6 (0.50) | CYP2D6KMT2AMEN1LMNATP53 | |
| SCHEMBL18531660 | 1.00 | CYP2D6 (0.50) | CYP2D6KMT2AMEN1LMNATP53 | |
| SCHEMBL80949 | 0.98 | — | — | |
| SCHEMBL83315 | 0.98 | — | — | |
| SCHEMBL1489684 | 0.98 | — | — | |
| SCHEMBL239626 | 0.93 | — | — | |
| SCHEMBL81766 | 0.93 | — | — | |
| SCHEMBL85855 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL7021993 | 0.91 | KMT2A (0.41) | CYP2D6KMT2AMEN1LMNATP53 | |
| Bicarbonate SCHEMBL16668716 | 0.87 | FDPS (0.49) | CYP2D6KMT2AMEN1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248586-B1 | PROCESS FOR PRODUCING AMIDINE SULFONIC ACID INTERMEDIATES FOR GUANIDINES | McNeilab, Inc. (US) | 1993-08-25 | — | — | EP | disclosed |
| US-4851094-A | OXIDIZING A THIOUREA WITH HYDROGEN PEROXIDE USING A MOLYBDENUM -CONTAINING CATALYST | MCNEILAB, INC. (US) | 1989-07-25 | — | — | US | disclosed |
| US-4781866-A | Process for producing amidine sulfonic acid intermediates for guanidines | MCNEILAB, INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0248586-A2 | Process for producing amidine sulfonic acid intermediates for guanidines | McNeilab, Inc. (US) | 1987-12-09 | — | — | EP | disclosed |
| US-4656291-A | OXIDIZING THIOUREA DERIVATIVE WITH HYDROGEN PEROXIDE IN PRESENCE OF MOLYBDENUM CATALYST | MCNEILAB, INC. (US) | 1987-04-07 | — | — | US | disclosed |