Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | UGT1A4 | P22310 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.31 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800253 | 0.82 | FDPS (0.39) | FDPSHSP90AA1CYP19A1CYP3A4CYP2C9 | |
| SCHEMBL6680541 | 0.77 | FDPS (0.53) | FDPSHSP90AA1CYP19A1CYP3A4CYP2C9 | |
| SCHEMBL10553128 | 0.77 | HSP90AA1 (0.62) | FDPSHSP90AA1CYP19A1CYP3A4CYP2C9 | |
| SCHEMBL10555615 | 0.77 | HSP90AA1 (0.62) | FDPSHSP90AA1CYP19A1CYP3A4CYP2C9 | |
| SCHEMBL9568076 | 0.77 | FDPS (0.40) | FDPSHSP90AA1CYP19A1CYP3A4CYP2C9 | |
| SCHEMBL9737979 | 0.74 | CYP3A4 (0.48) | HSP90AA1CYP19A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10505954 | 0.74 | FDPS (0.50) | FDPSHSP90AA1CYP19A1CYP3A4CYP2C9 | |
| SCHEMBL9517730 | 0.73 | FDPS (0.45) | FDPSHSP90AA1CYP19A1CYP3A4CYP2C9 | |
| SCHEMBL9517727 | 0.73 | FDPS (0.45) | FDPSHSP90AA1CYP19A1CYP3A4CYP2C9 | |
| SCHEMBL4640786 | 0.72 | FDPS (0.56) | FDPSHSP90AA1CYP19A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440949-B1 | Halogenallyl-azolyl derivatives | BAYER AG (DE) | 1993-10-27 | — | — | EP | disclosed |
| EP-0552546-A1 | Polybutylene terephthalate resin compositions | GE PLASTICS JAPAN LIMITED (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5122532-A | Bactericides, fungicides, algacides, slimicides; yeasts; protection for plants, cooling systems, textiles, paints and plastics | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-16 | — | — | US | disclosed |
| EP-0440949-A2 | Halogenallyl-azolyl derivatives | BAYER AG (DE) | 1991-08-14 | — | — | EP | disclosed |
| US-4483862-A | 2-(1H-1,2,4-triazol-1-yl)-1,1-bis-(perfluoro-alkyl)ethanol antifungal agents | PFIZER INC. (US) | 1984-11-20 | — | — | US | disclosed |