Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95819 | 0.87 | CA2 (0.55) | CA2PTPN1LMNAMAPT | |
| SCHEMBL95126 | 0.87 | CA2 (0.51) | CA2PTPN1LMNAMAPT | |
| SCHEMBL95405 | 0.85 | CA2 (0.49) | CA2PTPN1LMNA | |
| SCHEMBL94741 | 0.83 | CA2 (0.52) | CA2PTPN1LMNAMAPTMEN1 | |
| SCHEMBL13598466 | 0.83 | CA2 (0.51) | CA2PTPN1LMNAMAPT | |
| SCHEMBL94559 | 0.80 | CA2 (0.48) | CA2PTPN1LMNAMAPT | |
| SCHEMBL13598468 | 0.79 | CA2 (0.49) | CA2PTPN1LMNAMAPTMEN1 | |
| SCHEMBL13598464 | 0.79 | CA2 (0.47) | CA2PTPN1LMNAMEN1KMT2A | |
| SCHEMBL94320 | 0.78 | CA2 (0.46) | CA2PTPN1MEN1KMT2A | |
| SCHEMBL13598465 | 0.77 | CA2 (0.49) | CA2PTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | disclosed |