⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10825794 | 0.94 | — | — | |
| SCHEMBL10590608 | 0.91 | — | — | |
| SCHEMBL18025428 | 0.91 | — | — | |
| SCHEMBL8589427 | 0.91 | TRPV1 (0.40) | — | |
| SCHEMBL1660339 | 0.83 | — | — | |
| SCHEMBL1660336 | 0.83 | — | — | |
| SCHEMBL424751 | 0.82 | — | — | |
| SCHEMBL3914418 | 0.82 | — | — | |
| SCHEMBL13619244 | 0.82 | TSHR (0.47) | — | |
| SCHEMBL2155981 | 0.82 | TSHR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1030768-C | Primidine derivatives, process for preparing same and inhibitor for androgen | OTSUKA PHARMA CO LTD (JP) | 1996-01-24 | — | — | CN | disclosed |
| EP-0460111-B1 | PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS | EASTMAN KODAK CO (US) | 1993-12-08 | — | — | EP | disclosed |
| CN-1060844-A | Pyrimidine derivatives, its method for making and inhibitor for androgen | OTSUKA PHARMA CO LTD (JP) | 1992-05-06 | — | — | CN | disclosed |
| EP-0460111-A1 | PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS. | EASTMAN KODAK CO (US) | 1991-12-11 | — | — | EP | disclosed |
| US-4965361-A | CATALYTIC REACTION OF 4-SUBSTITUTED ARYL IODIDE WITH OLEFIN IN ESTER SOLVENT | EASTMAN KODAK COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0388322-A1 | Preparation of 4-substituted aryl olefins | EASTMAN KODAK COMPANY (US) | 1990-09-19 | — | — | EP | disclosed |
| WO-1990009973-A1 | PREPARATION OF 4-SUBSTITUTED ARYL OLEFINS | EASTMAN KODAK COMPANY (US) | 1990-09-07 | — | — | WO | disclosed |
| EP-0346882-A2 | Hydroxyalkylcysteine derivative and expectorant containing the same | SS PHARMACEUTICAL CO., LTD. (JP) | 1989-12-20 | — | — | EP | disclosed |