Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519444 | 0.90 | P4HTM (0.62) | P4HTMTSHRMEN1NPC1RAB9A | |
| SCHEMBL9516257 | 0.88 | P4HTM (0.64) | P4HTMTSHRMEN1NPC1RAB9A | |
| SCHEMBL9517336 | 0.87 | P4HTM (0.44) | P4HTMTSHRMEN1KMT2ACYSLTR1 | |
| SCHEMBL9517023 | 0.86 | P4HTM (0.62) | P4HTMTSHRMEN1NPC1RAB9A | |
| SCHEMBL9519091 | 0.84 | P4HTM (0.42) | P4HTMMCL1CASP1HDAC3 | |
| SCHEMBL9516016 | 0.83 | P4HTM (0.58) | P4HTMMCL1 | |
| SCHEMBL9517968 | 0.83 | P4HTM (0.69) | P4HTMTSHRMEN1NPC1RAB9A | |
| SCHEMBL9141420 | 0.78 | P4HTM (0.72) | P4HTMTSHRNPC1RAB9AMCL1 | |
| SCHEMBL9141396 | 0.78 | P4HTM (0.71) | P4HTMTSHRNPC1MCL1 | |
| SCHEMBL9018333 | 0.77 | P4HTM (0.64) | P4HTMTSHRMEN1KMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |