Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 3/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517241 | 0.88 | P4HTM (0.61) | P4HTMPTGS2PTGS1CASP3BCL2L1 | |
| SCHEMBL9517110 | 0.86 | P4HTM (0.61) | P4HTMPTGS2PTGS1CASP3BCL2L1 | |
| SCHEMBL9519091 | 0.85 | P4HTM (0.42) | P4HTMBCL2L1MCL1 | |
| SCHEMBL9515532 | 0.84 | P4HTM (0.61) | P4HTMPTGS2PTGS1CASP3BCL2L1 | |
| SCHEMBL9518099 | 0.83 | P4HTM (0.60) | P4HTMMCL1 | |
| SCHEMBL9515933 | 0.83 | P4HTM (0.55) | P4HTMPTGS2PTGS1CASP3BCL2L1 | |
| SCHEMBL9515571 | 0.81 | HDAC1 (0.46) | — | |
| SCHEMBL9518145 | 0.81 | P4HTM (0.61) | P4HTMPTGS2PTGS1CASP3BCL2L1 | |
| SCHEMBL9517200 | 0.80 | P4HTM (0.70) | P4HTMPTGS2PTGS1CASP3BCL2L1 | |
| SCHEMBL9519173 | 0.80 | P4HTM (0.58) | P4HTMPTGS2BCL2L1MCL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |