Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15756304 | 0.73 | NPC1 (0.52) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT | |
| Carbamic Acid SCHEMBL11116536 | 0.72 | ASAH1 (0.81) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL13092515 | 0.71 | ASAH1 (0.66) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL13092517 | 0.71 | ASAH1 (0.66) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL24361120 | 0.71 | SMN1; SMN2 (0.50) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL722366 | 0.70 | ASAH1 (0.57) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL29145117 | 0.70 | ASAH1 (0.57) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL10654951 | 0.70 | ASAH1 (0.90) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL670048 | 0.70 | ASAH1 (0.48) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL19848351 | 0.70 | KMT2A (0.53) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266950-B1 | Nor-statine and nor-cyclostatine polypeptides | PFIZER (US) | 1993-12-29 | — | — | EP | disclosed |
| US-5034376-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-4935405-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| US-4814342-A | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0266950-A2 | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1988-05-11 | — | — | EP | disclosed |