Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 16/20 | 0.78 |
| ▸ | PTGDR | Q13258 | 13/20 | 0.71 |
| ▸ | PDE2A | O00408 | 6/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763367 | 0.95 | TBXA2R (0.69) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9518400 | 0.91 | TBXA2R (0.75) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9518358 | 0.89 | TBXA2R (0.85) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9518078 | 0.88 | TBXA2R (0.60) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9277313 | 0.87 | TBXA2R (1.00) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9518334 | 0.85 | TBXA2R (0.79) | TBXA2RPTGDRPDE2A | |
| SCHEMBL10413594 | 0.85 | TBXA2R (0.96) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9518347 | 0.85 | TBXA2R (0.79) | TBXA2RPTGDRPDE2A | |
| SCHEMBL992425 | 0.83 | TBXA2R (0.82) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9521476 | 0.83 | TBXA2R (1.00) | TBXA2RPTGDRPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239306-B1 | TETRAHYDROCARBAZOLE ESTERS | MERCK FROSST CANADA INC. (CA) | 1993-06-02 | — | — | EP | claimed |
| EP-0234708-B1 | TETRAHYDROCARBAZOLE 1-ALKANOIC ACIDS | MERCK FROSST CANADA INC. (CA) | 1991-02-27 | — | — | EP | claimed |
| EP-0307077-A1 | Tetrahydrocarbazoles for the improvement of cyclosporin therapy | MERCK FROSST CANADA INC. (CA) | 1989-03-15 | — | — | EP | claimed |
| EP-0234708-A1 | Tetrahydrocarbazole 1-alkanoic acids | MERCK FROSST CANADA INC. (CA) | 1987-09-02 | — | — | EP | claimed |
| EP-0282077-B1 | Pyridyloxy derivatives | FUJIREBIO KK (JP) | 1993-11-10 | — | — | EP | disclosed |
| EP-0234708-B1 | TETRAHYDROCARBAZOLE 1-ALKANOIC ACIDS | MERCK FROSST CANADA INC. (CA) | 1991-02-27 | — | — | EP | disclosed |
| US-4988828-A | Antiulcer agents, antagonist for histamine H2 receptors | FUJIREBIO KABUSHIKI KAISHA (JP) | 1991-01-29 | — | — | US | disclosed |
| US-4977267-A | ANTISECRETORY AGENT | FUJIREBIO KABUSHIKI KAISHA (JP) | 1990-12-11 | — | — | US | disclosed |
| US-4912101-A | Containing a secondary amide, suflur group and a furan ring | FUJIREBIO KABUSHIKI KAISHA (JP) | 1990-03-27 | — | — | US | disclosed |
| EP-0318036-A2 | Phenoxypropyl derivatives | FUJIREBIO KABUSHIKI KAISHA (JP) | 1989-05-31 | — | — | EP | disclosed |
| EP-0307077-A1 | Tetrahydrocarbazoles for the improvement of cyclosporin therapy | MERCK FROSST CANADA INC. (CA) | 1989-03-15 | — | — | EP | disclosed |
| US-4808608-A | ANTIALLERGENS, HYPOTENSIVE AGENT, ANTICOAGULANT | MERCK & CO., INC. (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0300676-A2 | Tetrahydrocarbazole 1-alkanoic acids | MERCK FROSST CANADA INC. (CA) | 1989-01-25 | — | — | EP | disclosed |
| EP-0282077-A2 | Pyridyloxy derivatives | FUJIREBIO KABUSHIKI KAISHA (JP) | 1988-09-14 | — | — | EP | disclosed |
| EP-0234708-A1 | Tetrahydrocarbazole 1-alkanoic acids | MERCK FROSST CANADA INC. (CA) | 1987-09-02 | — | — | EP | disclosed |