Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 19/20 | 0.75 |
| ▸ | PTGDR | Q13258 | 17/20 | 0.73 |
| ▸ | PDE2A | O00408 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518236 | 0.91 | TBXA2R (0.78) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9518358 | 0.89 | TBXA2R (0.85) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9518253 | 0.88 | TBXA2R (0.59) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9518347 | 0.87 | TBXA2R (0.79) | TBXA2RPTGDRPDE2A | |
| SCHEMBL2763367 | 0.85 | TBXA2R (0.69) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9277313 | 0.85 | TBXA2R (1.00) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9518334 | 0.85 | TBXA2R (0.79) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9518365 | 0.85 | TBXA2R (0.75) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9518377 | 0.85 | TBXA2R (0.75) | TBXA2RPTGDRPDE2A | |
| SCHEMBL9518332 | 0.85 | TBXA2R (0.75) | TBXA2RPTGDRPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239306-B1 | TETRAHYDROCARBAZOLE ESTERS | MERCK FROSST CANADA INC. (CA) | 1993-06-02 | — | — | EP | claimed |
| EP-0307077-A1 | Tetrahydrocarbazoles for the improvement of cyclosporin therapy | MERCK FROSST CANADA INC. (CA) | 1989-03-15 | — | — | EP | claimed |
| EP-0307077-A1 | Tetrahydrocarbazoles for the improvement of cyclosporin therapy | MERCK FROSST CANADA INC. (CA) | 1989-03-15 | — | — | EP | disclosed |
| US-4808608-A | ANTIALLERGENS, HYPOTENSIVE AGENT, ANTICOAGULANT | MERCK & CO., INC. (US) | 1989-02-28 | — | — | US | disclosed |