Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787573 | 0.85 | MAPT (0.66) | MAPTTDP1LCKFYNKDM4E | |
| SCHEMBL1832009 | 0.85 | MAPT (0.49) | MAPTTDP1KDM4EHSD17B10MAPK1 | |
| SCHEMBL6648374 | 0.85 | MAPT (0.55) | MAPTTDP1LCKFYNKDM4E | |
| SCHEMBL10542808 | 0.84 | MAPT (0.46) | MAPTTDP1KDM4EHSD17B10MAPK1 | |
| SCHEMBL29378830 | 0.82 | MAPT (0.72) | MAPTTDP1LCKFYNKDM4E | |
| SCHEMBL3189109 | 0.82 | MAPT (0.72) | MAPTTDP1LCKFYNKDM4E | |
| SCHEMBL9353417 | 0.81 | MAPT (0.61) | MAPTTDP1LCKFYNKDM4E | |
| SCHEMBL17339024 | 0.81 | MAPT (0.51) | MAPTTDP1LCKFYNKDM4E | |
| SCHEMBL17142285 | 0.80 | ALDH1A1 (0.54) | MAPTTDP1LCKFYNKDM4E | |
| SCHEMBL28283707 | 0.80 | TDP1 (0.50) | MAPTTDP1LCKFYNKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |