SCHEMBL9518610

SCHEMBL9518610

N#Cc1c(Cl)c(Cl)n(Cc2ccccc2)c1-c1ccc(Cl)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 4/20 0.45
AR P10275 1/20 0.43
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
HPGD P15428 2/20 0.42
PPARG P37231 1/20 0.42
NCOA2 Q15596 1/20 0.42
NCOA1 Q15788 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
NCOA3 Q9Y6Q9 1/20 0.42
CNR1 P21554 2/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CXCR2 P25025 1/20 0.39
PDE9A O76083 1/20 0.39
PDE1C Q14123 1/20 0.39
SIGMAR1 Q99720 1/20 0.38
ACHE P22303 2/20 0.37
NRP1 O14786 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10589846 0.86 KDM4C (0.36) CCR2ARALDH1A1KDM4EHPGD
SCHEMBL7500290 0.83 AHR (0.37) CCR2ALDH1A1KDM4EHPGDNPSR1
SCHEMBL9056032 0.82 AHR (0.36) CCR2ALDH1A1HPGDMEN1KMT2A
SCHEMBL9336008 0.82 AHR (0.36) CCR2ARKDM4EHPGD
SCHEMBL9228443 0.80 DCUN1D1 (0.37) CCR2HPGDNPSR1MEN1KMT2A
SCHEMBL10590897 0.80 MEN1 (0.35) CCR2ARALDH1A1KDM4EHPGD
SCHEMBL7505132 0.78 NPC1 (0.39) CCR2ALDH1A1KDM4EHPGDCNR1
SCHEMBL9222542 0.78 AHR (0.36) CCR2KDM4EHPGD
SCHEMBL9222935 0.77 AHR (0.39) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL10590741 0.77 HPGD (0.34) ARALDH1A1KDM4EHPGDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0312723-B1 Method of and bait compositions for controlling mollusks AMERICAN CYANAMID CO (US) 1993-12-22 EP claimed
US-4929634-A ARYLPYRROLE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1990-05-29 US claimed
EP-0312723-A2 Method of and bait compositions for controlling mollusks AMERICAN CYANAMID COMPANY (US) 1989-04-26 EP claimed
US-4929634-A ARYLPYRROLE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1990-05-29 US disclosed
EP-0347488-A1 Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1989-12-27 EP disclosed
EP-0312723-A2 Method of and bait compositions for controlling mollusks AMERICAN CYANAMID COMPANY (US) 1989-04-26 EP disclosed