SCHEMBL9056032

SCHEMBL9056032

N#CCn1c(Cl)c(Cl)c(C#N)c1-c1ccc(Cl)c(Cl)c1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.36
HPGD P15428 2/20 0.36
LMNA P02545 1/20 0.36
CYP1B1 Q16678 1/20 0.36
KMO O15229 2/20 0.35
MAPK14 Q16539 1/20 0.35
IDO1 P14902 1/20 0.34
ALOX15 P16050 2/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ADORA2A P29274 2/20 0.33
ADORA1 P30542 2/20 0.33
CCR2 P41597 1/20 0.32
ABL1 P00519 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9228443 0.89 DCUN1D1 (0.37) AHRHPGDLMNACYP1B1KMO
SCHEMBL7500290 0.87 AHR (0.37) AHRHPGDLMNACYP1B1KMO
SCHEMBL9222542 0.87 AHR (0.36) AHRHPGDLMNACYP1B1KMO
SCHEMBL9336008 0.86 AHR (0.36) AHRHPGDLMNACYP1B1KMO
SCHEMBL9055243 0.84 USP2 (0.38) HPGDLMNAALOX15MEN1USP2
SCHEMBL10590897 0.83 MEN1 (0.35) AHRHPGDLMNACYP1B1KMO
SCHEMBL9518610 0.82 CCR2 (0.45) HPGDMEN1ALDH1A1KMT2ACCR2
SCHEMBL10590741 0.80 HPGD (0.34) AHRHPGDLMNACYP1B1KMO
SCHEMBL9225473 0.80 ADORA1 (0.33) AHRHPGDLMNACYP1B1KMO
SCHEMBL9059293 0.78 KIF11 (0.41) HPGDLMNAMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0426948-B1 Arylpyrrole insecticidal acaricidal and nematicidal agents and methods AMERICAN CYANAMID CO (US) 1996-05-08 EP disclosed
EP-0426948-A1 Arylpyrrole insecticidal acaricidal and nematicidal agents and methods AMERICAN CYANAMID COMPANY (US) 1991-05-15 EP disclosed