Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518656 | 1.00 | ARG1 (0.45) | ARG1DRD3SLC6A3GRIN2DGRIN3B | |
| SCHEMBL9518643 | 1.00 | ARG1 (0.45) | ARG1DRD3SLC6A3GRIN2DGRIN3B | |
| SCHEMBL23214633 | 0.87 | GRIN2D (0.41) | ARG1DRD3SLC6A3GRIN2DGRIN3B | |
| SCHEMBL9602233 | 0.84 | ARG1 (0.43) | ARG1DRD3SLC6A3GRIN2DGRIN3B | |
| SCHEMBL5516670 | 0.81 | DRD3 (0.46) | ARG1DRD3SLC6A3GRIN2DGRIN3B | |
| SCHEMBL5527376 | 0.79 | DRD3 (0.45) | ARG1DRD3SLC6A3GRIN2DGRIN3B | |
| SCHEMBL9602221 | 0.78 | MEN1 (0.68) | ARG1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9602209 | 0.78 | MEN1 (0.68) | ARG1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9602200 | 0.78 | MEN1 (0.68) | ARG1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2065284 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330353-B1 | TETRAZOLE EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1993-04-07 | — | — | EP | disclosed |
| US-4968678-A | NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0330353-A1 | Tetrazole excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1989-08-30 | — | — | EP | disclosed |