Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800574 | 1.00 | THRB (0.36) | THRBMEN1KMT2AMMP2MMP9 | |
| SCHEMBL9514928 | 1.00 | THRB (0.36) | THRBMEN1KMT2AMMP2MMP9 | |
| SCHEMBL9516654 | 1.00 | THRB (0.36) | THRBMEN1KMT2AMMP2MMP9 | |
| SCHEMBL9515475 | 1.00 | THRB (0.36) | THRBMEN1KMT2AMMP2MMP9 | |
| SCHEMBL9514945 | 0.81 | THRB (0.39) | THRBMEN1KMT2AMMP2MMP9 | |
| SCHEMBL9800579 | 0.79 | — | — | |
| SCHEMBL9516453 | 0.79 | — | — | |
| SCHEMBL9516583 | 0.79 | — | — | |
| SCHEMBL9514896 | 0.74 | THRB (0.34) | THRBMEN1KMT2AMMP2MMP9 | |
| SCHEMBL9514919 | 0.74 | THRB (0.34) | THRBMEN1KMT2AMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341409-B1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-12-29 | — | — | EP | claimed |
| EP-0341409-B1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-12-29 | — | — | EP | disclosed |