Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 13/20 | 0.39 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518759 | 1.00 | LMNA (0.40) | LMNAKMT2ATLR4LY96CYP3A4 | |
| SCHEMBL9518870 | 0.92 | LMNA (0.39) | LMNAKMT2ATLR4LY96CYP3A4 | |
| SCHEMBL9518876 | 0.92 | LMNA (0.39) | LMNAKMT2ATLR4LY96CYP3A4 | |
| SCHEMBL9518931 | 0.87 | TLR4 (0.39) | LMNAKMT2ATLR4LY96CYP3A4 | |
| SCHEMBL9518924 | 0.87 | TLR4 (0.39) | LMNAKMT2ATLR4LY96CYP3A4 | |
| SCHEMBL10530171 | 0.86 | TLR4 (0.38) | TLR4LY96 | |
| SCHEMBL9637333 | 0.86 | TLR4 (0.38) | TLR4LY96 | |
| SCHEMBL9520386 | 0.86 | TLR4 (0.36) | TLR4LY96CYP3A4MAPTCYP2C9 | |
| SCHEMBL9518719 | 0.85 | TLR4 (0.37) | TLR4LY96 | |
| SCHEMBL9637604 | 0.85 | TLR4 (0.32) | TLR4LY96CYP3A4MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330715-B1 | DISACCHARIDE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-5134230-A | Disaccharide Antitumor Agent Intermediates | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |
| US-5006647-A | Antitumor agents | DAIICHI SEIYAKU CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |