⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15043324 | 1.00 | — | — | |
| SCHEMBL951882 | 1.00 | — | — | |
| SCHEMBL18752199 | 0.80 | POLB (0.48) | — | |
| SCHEMBL7345262 | 0.78 | TDP1 (0.52) | — | |
| SCHEMBL7345258 | 0.78 | TDP1 (0.52) | — | |
| SCHEMBL13887197 | 0.77 | TDP1 (0.46) | — | |
| SCHEMBL25246733 | 0.75 | — | — | |
| SCHEMBL263813 | 0.75 | — | — | |
| SCHEMBL1430406 | 0.75 | — | — | |
| SCHEMBL12864549 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384096-A | Preparation method of difluoro pyrazole acid | 山东国邦药业有限公司 | 2024-01-12 | — | — | CN | claimed |
| EP-0873746-A2 | Dyestuff for keratinous fibers | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-10-28 | — | — | EP | claimed |
| JP-3038583-A | — | — | None | — | — | JP | disclosed |
| US-20260116868-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2026-04-30 | — | — | US | disclosed |
| EP-4720055-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | Arcus Biosciences, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| US-20250320213-A1 | Nitrogen-Containing Heterocyclic Compounds | PFIZER INC. (US) | 2025-10-16 | — | — | US | disclosed |
| WO-2025215579-A1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS | PFIZER INC. (US) | 2025-10-16 | — | — | WO | disclosed |
| WO-2025076299-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2025-04-10 | — | — | WO | disclosed |
| CN-114008065-B | Glycyrrhetinic acid derivatives for the treatment of hyperkalemia | 阿德利克斯股份有限公司 | 2025-03-11 | — | — | CN | disclosed |
| US-20250011318-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2025-01-09 | — | — | US | disclosed |
| WO-2024243502-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2024-11-28 | — | — | WO | disclosed |
| EP-0608725-B1 | Process for preparing aminomethylene compounds | BAYER AG (DE) | 2000-05-17 | — | — | EP | disclosed |
| EP-0873746-A2 | Dyestuff for keratinous fibers | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5401869-A | Process for the preparation of aminomethylene compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1995-03-28 | — | — | US | disclosed |
| EP-0406839-B1 | Process for the preparation of 1-(4-tetrahydropyranyl) or 1-(4-tetrahydrothiopyranyl)-prop-1-en-3-ones | BASF AG (DE) | 1995-02-01 | — | — | EP | disclosed |
| EP-0608725-A2 | Process for preparing aminomethylene compounds | BAYER AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| US-5221753-A | PREPARATION OF 1-(4-TETRAHYDROPYRANYL)- OR 1-(4-TETRAHYDROTHIOPYRANYL)PROP-1-EN-3-ONES | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |
| JP-H0338583-A | PRODUCTION OF 1-(4-TETRAHYDROPYRANYL)-1-BUTEN-3-ONE | NIPPON SODA CO LTD | 1991-02-19 | — | — | JP | disclosed |
| EP-0406839-A2 | Process for the preparation of 1-(4-tetrahydropyranyl) or 1-(4-tetrahydrothiopyranyl)-prop-1-en-3-ones | BASF Aktiengesellschaft (DE) | 1991-01-09 | — | — | EP | disclosed |
| EP-0322616-A2 | Novel 5(and/or 6)substituted 2-(2-imidazolin-2-yl)nicotinic acids, esters and salts, useful as herbicidal agents and nivel intermediates for the preparation of said nicotinic acids, esters and salts | AMERICAN CYANAMID COMPANY (US) | 1989-07-05 | — | — | EP | disclosed |