Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | PARP1 | P09874 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | HTR7 | P34969 | 2/20 | 0.60 |
| ▸ | HRH1 | P35367 | 1/20 | 0.60 |
| ▸ | DRD4 | P21917 | 2/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520094 | 0.96 | HTT (0.69) | HTTPOLBPARP1DRD2DRD3 | |
| SCHEMBL9518726 | 0.94 | DRD2 (0.67) | HTTPOLBPARP1DRD2DRD3 | |
| SCHEMBL29370038 | 0.88 | HTT (0.70) | HTTPOLBPARP1DRD2DRD3 | |
| SCHEMBL7006523 | 0.82 | POLB (1.00) | POLB | |
| SCHEMBL15063202 | 0.81 | HTT (1.00) | HTTDRD2DRD4 | |
| SCHEMBL31010306 | 0.81 | HTT (1.00) | HTTDRD2DRD4 | |
| SCHEMBL22633621 | 0.81 | HTT (1.00) | HTTDRD2DRD4 | |
| SCHEMBL5337358 | 0.80 | CHRNA7 (0.62) | POLBPARP1DRD2DRD3HTR1A | |
| SCHEMBL7856311 | 0.80 | POLB (0.96) | POLB | |
| SCHEMBL7856315 | 0.80 | POLB (0.96) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350467-B1 | Pharmacologically active benzimidazole derivatives | DOMPE FARMACEUTICI SPA (IT) | 1993-12-29 | — | — | EP | disclosed |
| US-4971980-A | ANTIHISTAMINES | DOMPE FARMACEUTICI S.P.A. (IT) | 1990-11-20 | — | — | US | disclosed |