Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decanoic Acid SCHEMBL9519013 | 1.00 | CYP1A2 (0.51) | CYP1A2HDAC1HDAC8CCKBRUTS2R | |
| Decanoic Acid SCHEMBL9613836 | 0.84 | HDAC1 (0.45) | HDAC1CCKBRUTS2RCYSLTR2CYSLTR1 | |
| Decanoic Acid SCHEMBL9519021 | 0.77 | CYP1A2 (0.53) | CYP1A2HDAC1HDAC8CCKBRCYP2D6 | |
| Citric Acid SCHEMBL9520797 | 0.74 | SLC13A5 (0.55) | CYP1A2HDAC1HDAC8UTS2RCYP2D6 | |
| Citric Acid SCHEMBL9520794 | 0.74 | SLC13A5 (0.55) | CYP1A2HDAC1HDAC8UTS2RCYP2D6 | |
| SCHEMBL10439755 | 0.73 | CYP1A2 (0.87) | CYP1A2HDAC1HDAC8CYP2D6CYP2C19 | |
| SCHEMBL10439620 | 0.73 | CYP1A2 (0.87) | CYP1A2HDAC1HDAC8CYP2D6CYP2C19 | |
| SCHEMBL710798 | 0.73 | CYP1A2 (0.87) | CYP1A2HDAC1HDAC8CYP2D6CYP2C19 | |
| SCHEMBL8434872 | 0.73 | CYP1A2 (0.87) | CYP1A2HDAC1HDAC8CYP2D6CYP2C19 | |
| SCHEMBL2107915 | 0.73 | CYP1A2 (0.87) | CYP1A2HDAC1HDAC8CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318234-B1 | IMPROVEMENTS IN OR RELATING TO SELECTIVE SEROTONIN UPTAKE INHIBITORS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4876282-A | ANTIDEPRESSANT, DIETETICS, ANTIALCOHOLISM AGENT | ELI LILLY AND COMPANY (US) | 1989-10-24 | — | — | US | disclosed |
| EP-0318234-A2 | Improvements in or relating to selective serotonin uptake inhibitors | ELI LILLY AND COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |