SCHEMBL9519045

SCHEMBL9519045

Cc1nc(S)cc(C(F)(F)F)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.44
HSP90AB1 P08238 1/20 0.44
TSHR P16473 2/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CRHBP P24387 1/20 0.35
CYP2C19 P33261 1/20 0.35
CRHR2 Q13324 1/20 0.35
TRPV4 Q9HBA0 1/20 0.34
HSD17B10 Q99714 4/20 0.33
HPGD P15428 3/20 0.33
SDHB P21912 3/20 0.33
ATM Q13315 2/20 0.33
KDM4E B2RXH2 2/20 0.33
KMT2A Q03164 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
ALDH1A1 P00352 2/20 0.32
PHGDH O43175 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10271825 0.84 HSP90AA1 (0.52) HSP90AA1HSP90AB1TSHRCYP3A4CYP2D6
SCHEMBL21212748 0.83 HSP90AA1 (0.44) HSP90AA1HSP90AB1TSHRCYP3A4CYP2D6
SCHEMBL27892045 0.80 HSP90AA1 (0.31) HSP90AA1HSP90AB1
SCHEMBL14927263 0.77 HSP90AA1 (0.63) HSP90AA1HSP90AB1TSHRCYP3A4CYP2D6
Ammonia Solution, Strong SCHEMBL15795498 0.76 HSP90AA1 (0.61) HSP90AA1HSP90AB1TSHRCYP3A4CYP2D6
SCHEMBL11740480 0.75
SCHEMBL24355364 0.74 HSP90AA1 (0.53) HSP90AA1HSP90AB1TSHRCYP3A4CYP2D6
SCHEMBL603692 0.74 HSP90AA1 (0.44) HSP90AA1HSP90AB1TSHRCYP3A4CYP2D6
SCHEMBL18248761 0.74 HSP90AA1 (0.44) HSP90AA1HSP90AB1TSHRCYP3A4CYP2D6
SCHEMBL28853428 0.74 HSP90AA1 (0.44) HSP90AA1HSP90AB1TSHRCYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0407873-B1 PROCESS FOR PEST CONTROL USING PYRIMIDINS BASF Aktiengesellschaft (DE) 1993-09-29 EP disclosed
US-5106852-A Insecticides, miticides BASF AKTIENGESELLSCHAFT (DE) 1992-04-21 US disclosed
US-5047408-A APPLYING TO COMBAT CATERPILLARS, MOTHS, ACARINA AND ETC.; MITICIDES BASF AKTIENGESELLSCHAFT (DE) 1991-09-10 US disclosed
EP-0407873-A1 Process for pest control using pyrimidins BASF Aktiengesellschaft (DE) 1991-01-16 EP disclosed