Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10271825 | 0.84 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1HPGDATML3MBTL1 | |
| SCHEMBL19711969 | 0.83 | — | — | |
| SCHEMBL2719104 | 0.80 | HSD17B10 (0.34) | CYP3A4CYP2C19TSHRALDH1A1POLB | |
| SCHEMBL14927263 | 0.77 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1HPGDATML3MBTL1 | |
| SCHEMBL1258669 | 0.77 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1HPGDATML3MBTL1 | |
| SCHEMBL9519023 | 0.76 | CYP2C19 (0.35) | HSP90AA1HSP90AB1HPGDATML3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL15795498 | 0.76 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1HPGDATML3MBTL1 | |
| SCHEMBL601042 | 0.76 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1HPGDATML3MBTL1 | |
| SCHEMBL125608 | 0.75 | — | — | |
| SCHEMBL601813 | 0.75 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1CYP3A4CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126147-B | Pyrimidine substituted 1,3, 4-oxadiazole derivative, preparation method and application | 贵阳学院 | 2026-05-15 | — | — | CN | disclosed |
| CN-117886807-A | Ferulic acid derivative containing 1,3, 4-oxadiazole and trifluoromethyl pyrimidine | 贵阳学院 | 2024-04-16 | — | — | CN | disclosed |
| US-11935803-B2 | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-03-19 | — | — | US | disclosed |
| CN-117126147-A | Pyrimidine substituted 1,3, 4-oxadiazole derivative, preparation method and application | 贵阳学院 | 2023-11-28 | — | — | CN | disclosed |
| CN-112004845-B | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate, and semiconductor device | 三菱瓦斯化学株式会社 | 2022-05-31 | — | — | CN | disclosed |
| US-20220125780-A1 | SUBSTITUTED TETRAHYDROQUINOLINONE COMPOUNDS AS ROR GAMMA MODULATORS | AURIGENE ONCOLOGY LIMITED (IN) | 2022-04-28 | — | — | US | disclosed |
| CN-110003117-B | Ferulic acid amide derivative containing trifluoromethylpyrimidine, and preparation and application thereof | 贵阳学院 | 2022-04-19 | — | — | CN | disclosed |
| US-11229636-B2 | Substituted tetrahydroquinolinone compounds as ROR gamma modulators | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2022-01-25 | — | — | US | disclosed |
| US-20210277221-A1 | RESIN COMPOSITION, LAMINATE, SEMICONDUCTOR WAFER WITH RESIN COMPOSITION LAYER, SUBSTRATE FOR MOUNTING SEMICONDUCTOR WITH RESIN COMPOSITION LAYER AND SEMICONDUCTOR DEVICE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-09-09 | — | — | US | disclosed |
| EP-3845526-A1 | METHOD FOR THE PREPARATION OF TETRAHYDROQUINOLINONE COMPOUNDS HAVING ROR-GAMMA MODULATING ACTIVITY | Aurigene Discovery Technologies Limited (IN) | 2021-07-07 | — | — | EP | disclosed |
| EP-2432780-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | Sumitomo Chemical Company, Limited (JP) | 2012-03-28 | — | — | EP | disclosed |
| US-20120041009-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20120041009-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20120041009-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| WO-2010134478-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-25 | — | — | WO | disclosed |
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-05-13 | — | — | US | disclosed |
| CN-1473155-A | Pyrimidine derivatives and herbicides containing the same | ס������ũҩ��ʽ���� | 2004-02-04 | — | — | CN | disclosed |
| EP-1333029-A1 | PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-0224217-B1 | PHOSPHORIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR COMBATTING PESTS | BASF Aktiengesellschaft (DE) | 1989-06-21 | — | — | EP | disclosed |
| EP-0224217-A1 | Phosphoric acid derivatives, process for their preparation and their use for combatting pests | BASF Aktiengesellschaft (DE) | 1987-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11229636-B2 | Substituted tetrahydroquinolinone compounds as ROR gamma modulators | RORC, RORA, RORB | HSP90AA1 1600/4885HSP90AB1 1590/4885HPGD 915/4885 |
| US-20120041009-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | TYMP, DPYD, TYMS | HSP90AA1 3094/4885HSP90AB1 3128/4885HPGD 1037/4885 |
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | DDX41, CBR3, DPYD | HSP90AA1 3014/4885HSP90AB1 3068/4885HPGD 2663/4885 |
| US-20220125780-A1 | SUBSTITUTED TETRAHYDROQUINOLINONE COMPOUNDS AS ROR GAMMA MODULATORS | RORC, RORA, RORB | HSP90AA1 1600/4885HSP90AB1 1590/4885HPGD 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.