Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PPOX | P50336 | 1/20 | 0.30 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.30 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522911 | 0.88 | NPC1 (0.31) | MAPTALDH1A1 | |
| SCHEMBL9706612 | 0.88 | LMNA (0.35) | LMNAMAPTHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL9521572 | 0.87 | LMNA (0.34) | LMNAMAPTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL9521004 | 0.86 | NOTUM (0.31) | HPGDSMN1; SMN2 | |
| SCHEMBL9706624 | 0.82 | LMNA (0.34) | LMNAMAPTHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL10411538 | 0.81 | LMNA (0.34) | LMNAMAPTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL10410791 | 0.80 | LMNA (0.33) | LMNAMAPTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL9468954 | 0.78 | MAPT (0.35) | LMNAMAPTHPGDSMN1; SMN2KMT2A | |
| SCHEMBL10645885 | 0.78 | MAPT (0.35) | LMNAMAPTHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL10647266 | 0.76 | MAPT (0.34) | LMNAMAPTHPGDSMN1; SMN2BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323487-B1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | claimed |
| US-4941909-A | HERBICIDES, PYRIMIDONE BENZOATES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-17 | — | — | US | disclosed |