Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azepane SCHEMBL1450973 | 1.00 | ALDH1A1 (0.60) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Piperidine SCHEMBL15517892 | 0.97 | ALDH1A1 (0.56) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Piperidine SCHEMBL15511100 | 0.97 | ALDH1A1 (0.56) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Piperidine SCHEMBL15511101 | 0.97 | ALDH1A1 (0.56) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Azepane SCHEMBL5164365 | 0.97 | ALDH1A1 (0.56) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Piperidine SCHEMBL15517893 | 0.97 | ALDH1A1 (0.56) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Pyrrolidine SCHEMBL11618713 | 0.97 | ALDH1A1 (0.53) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Piperidine SCHEMBL15570570 | 0.94 | ALDH1A1 (0.53) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Piperidine SCHEMBL15572305 | 0.94 | ALDH1A1 (0.53) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Piperidine SCHEMBL28020374 | 0.94 | ALDH1A1 (0.53) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330353-B1 | TETRAZOLE EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1993-04-07 | — | — | EP | disclosed |
| EP-0330353-A1 | Tetrazole excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1989-08-30 | — | — | EP | disclosed |