Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL10827455 | 0.98 | CYP2C19 (0.63) | CYP2C19CYP2C9MAPTNPSR1GAA | |
| SCHEMBL8391995 | 0.83 | ALDH1A1 (0.55) | CYP2C19CYP2C9MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL8518308 | 0.83 | ALDH1A1 (0.59) | CYP2C19CYP2C9MAPTGAASMN1; SMN2 | |
| SCHEMBL11165050 | 0.83 | ALDH1A1 (0.53) | CYP2C19CYP2C9MAPTNPSR1GAA | |
| SCHEMBL11473652 | 0.83 | SMN1; SMN2 (0.55) | MAPTGAASMN1; SMN2HPGDLMNA | |
| Iodide SCHEMBL10827369 | 0.81 | ALDH1A1 (0.58) | CYP2C19CYP2C9MAPTGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11483908 | 0.81 | KMT2A (0.58) | CYP2C19CYP2C9MAPTGAASMN1; SMN2 | |
| SCHEMBL14448354 | 0.81 | ALDH1A1 (0.60) | MAPTNPSR1GAASMN1; SMN2HPGD | |
| SCHEMBL10785302 | 0.81 | MAPT (0.56) | CYP2C19CYP2C9MAPTLMNAALDH1A1 | |
| Iodide SCHEMBL10827361 | 0.80 | ALDH1A1 (0.61) | CYP2C19MAPTGAASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248586-B1 | PROCESS FOR PRODUCING AMIDINE SULFONIC ACID INTERMEDIATES FOR GUANIDINES | McNeilab, Inc. (US) | 1993-08-25 | — | — | EP | disclosed |
| US-4851094-A | OXIDIZING A THIOUREA WITH HYDROGEN PEROXIDE USING A MOLYBDENUM -CONTAINING CATALYST | MCNEILAB, INC. (US) | 1989-07-25 | — | — | US | disclosed |
| US-4781866-A | Process for producing amidine sulfonic acid intermediates for guanidines | MCNEILAB, INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0248586-A2 | Process for producing amidine sulfonic acid intermediates for guanidines | McNeilab, Inc. (US) | 1987-12-09 | — | — | EP | disclosed |
| US-4693850-A | Methane sulfonic acid derivatives | MCNEILAB, INC. (US) | 1987-09-15 | — | — | US | disclosed |
| US-4656291-A | OXIDIZING THIOUREA DERIVATIVE WITH HYDROGEN PEROXIDE IN PRESENCE OF MOLYBDENUM CATALYST | MCNEILAB, INC. (US) | 1987-04-07 | — | — | US | disclosed |
| US-4656270-A | Process for producing guanidines such as linogliride | MCNEILAB, INC. (US) | 1987-04-07 | — | — | US | disclosed |
| EP-0195620-A2 | Process for producing guanidines such as linogliride and process for intermediates | McNeilab, Inc. (US) | 1986-09-24 | — | — | EP | disclosed |